Novel Idea: Virulence-Based Therapy Against Helicobacter pylori Infection (Smart Therapy)

Novel Idea: Virulence-Based Therapy Against Helicobacter pylori Infection (Smart Therapy)

INTRODUCTION Helicobacter pylori (H. pylori) is a Gramnegative, spiral, and microaerophilic bacterium, which can usually persist lifelong in gastric mucosa if not treated efficiently. H. pylori infection plays an undeniable role in the development of different gastroduodenal diseases, while its eradication cures ulcer disease and also prevents occurrence of gastric cancer (1–3). At the beginnin...

Which Therapy for Helicobacter pylori Infection?

Rescue Therapy for Helicobacter pylori Infection 2012

Helicobacter pylori infection is the main cause of gastritis, gastroduodenal ulcer disease, and gastric cancer. After 30 years of experience in H. pylori treatment, however, the ideal regimen to treat this infection has still to be found. Nowadays, apart from having to know well first-line eradication regimens, we must also be prepared to face treatment failures. In designing a treatment strate...

efficacy of standard triple therapy versus bismuth-based quadruple therapy for eradication of helicobacter pylori infection

helicobacter pylori is the main cause of gastric ulcer, adenocarcinoma and mucosa-associated lymphoid tissue (malt) lymphoma. up to now, different regimens have been used for helicobacter pylori (h.pylori) eradication to find the most potent and cost-effective regimen with less side effects. the aim of this study was to investigate the efficacy of standard triple therapy versus quadruple therap...

Antibacterial activities of Galla rhois extracts against Helicobacter pylori infection

In this study, a medicinal plant, Galla rhois (GR), was examined and screened for its anti-Helicobacter pylori activity. Galla rhois was extracted with 70% ethanol. Inhibitory zone tests, as in vitro assays, and an in vivo study using a Mongolian gerbil (Meriones unguiculatus) model were performed. The safety of the GR extract was then evaluated in an animal study. The Galla rhois extract demon...